This study provides supplemental data to support the study on Optimizing Genomic-Enabled Prediction: A Feature Weighting Approach for Enhancing within Family Accuracy.
Potato breeding efficiency can be improved by increasing the reliability of selection and identifying promising germplasm for crossing. The data provided in these datasets were used to compare the prediction accuracy of genomic-estimated breeding values for several potato (Solanum tuberosum L.) breeding clones and released cultivars evaluated in three locations in northern and southern Sweden. The analysis included several traits such as tuber starch percentage and total tuber weight. Results of the analyses are reported in an accompanying journal article.
Genomic prediction models may be used in plant breeding pipelines. They are often calibrated using multi-generation data and there is an open question of whether all available data or a subset of it should be used to calibrate genomic prediction models. Therefore, a study was undertaken to determine whether combining sparse selection indexes (SSIs) and kernel methods could further improve prediction accuracy when training genomic models using multi-generation data. This dataset contains the genotypic and phenotypic data from CIMMYT maize doubled haploid lines that were used to perform the analyses. The results of the analyses are presented in the accompanying article.
In this paper we cover multi-trait prediction of grain yield (GY), days to heading (DH) and plant height (PH) of 270 durum wheat lines that were evaluated in 43 environments (location-year combinations) in Bologna, Italy. The results of the multi-trait deep learning method also were compared with univariate predictions of the genomic best linear unbiased predictor (GBLUP) method and the univariate counterpart of the multi-trait deep learning method. All models were implemented with and without the genotype×environment interaction term. We found that the best predictions were observed without the genotype×environment interaction term in the univariate and multivariate deep learning methods, but under the GBLUP method, the best predictions were observed taking into account the interaction term. We also found that in general the best predictions were observed under the GBLUP model but the predictions of the multi-trait deep learning model were very similar to those of the GBLUP model.
In genomic prediction deep learning artificial neural network are part of machine learning methods that incorporate parametric, non-parametric and semi-parametric statistical models. Kernel methods are seeing more flexible, and easier to interpret than neural networks. Kernel methods used in genomic predictions comprise the linear genomic best linear unbiased predictor (GBLUP) kernel (GB) and the Gaussian kernel (GK). These kernels have being used with two statistical models, single environment and genomic × environment (GE) models. Recently near infrared spectroscopy (NIR) has being used as phenotype method for prediction of unobserved line performance in plant breeding trials. In this study, we used a non-linear Arc-cosine kernel (AK) that emulates deep learning artificial neural network. We compared AK prediction accuracy with GB and GK kernel methods in four genomic data sets one of them including also pedigree (ABLUP) and NIR (NBLUP) information. Results show that for all four data sets AK and GK kernels gave higher prediction accuracy than the linear GB kernel for single environment as well as GE multi-environment models. In addition, AK gave similar or slightly higher prediction accuracy than the GK kernel.
Machine learning (ML) is a field of computer science that uses statistical techniques to give computer systems the ability to "learn" (i.e., progressively improve performance on a specific task) from data, without being explicitly programmed to do this. ML is closely related to (and often overlaps with) computational statistics, which also focuses on making predictions through the use of computers. In general, ML explores algorithms that can learn from current data and make predictions on new data, through building a model from sample inputs. The field of statistics and ML had a root in common and will continue to come closer together in the future. In this paper we explore the novel deep learning (DL) methodology in the context of genomic selection. DL models with densely connected network architecture were compared with one of the most often used genome-enabled prediction models genomic best linear unbiased prediction (GBLUP). We used nine published real genomic data sets to compare the models and obtain a “meta picture” of the performance of DL models with a densely connected network architecture.